Dynamism has a downside

Dynamism Gloom and Doom?

1 This work is supported in part by AFOSR (F49620-98-1-0217) and NSF (CCR-9988320). Abstract. In the areas of application integration, mobility, and agent technology, dynamism is an increasingly desirable quality. However, deploying dynamism is problematic due to constraints on and limitations of the applications and middleware used in such distributed systems. In order to realize dynamism in t...

The Downside of Defaults

Protein dynamism and evolvability.

The traditional view that proteins possess absolute functional specificity and a single, fixed structure conflicts with their marked ability to adapt and evolve new functions and structures. We consider an alternative, "avant-garde view" in which proteins are conformationally dynamic and exhibit functional promiscuity. We surmise that these properties are the foundation stones of protein evolva...

Downside of assessment success

The increase in the amount of high quality research demonstrates that the UK's universities are delivering even better research than five years ago. " But Roderick Floud, president of Universities UK and vice-chancellor of Guildhall University, called on the government to fund the improved results. " These results show that our universities are contributing at a world-class level, and we urge t...

Measures of downside risk

The paper characterizes a family of downside risk measures. They depend on a target value and a parameter reflecting the attitude towards downside risk. The indicators are probability weighted −order means of possible shortfalls. They form a subclass of the measures intro¬duced by Stone (1973) and are related to the measures proposed by Fishburn (1977). The axiomatization is based on some prope...